Estimating the causal tissues for complex traits and diseases
NATURE GENETICS(2017)
摘要
This study presents a new approach to estimate the tissues contributing to the genetic causality for complex traits and diseases. The method assesses tissue sharing of eQTLs among 44 tissues and then uses these tissue-sharing estimates to infer the tissues where trait-associated variants likely exert their function.
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关键词
Transcriptomics
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