Maternal consumption of high-fat diet and grape juice modulates global histone H4 acetylation levels in offspring hippocampus: a preliminary study.

Luciana Kneib Gonçalves,Ivy Reichert Vital da Silva,Laura Reck Cechinel,Marina Rocha Frusciante,Alexandre Silva de Mello,Viviane Rostirola Elsner,Claudia Funchal,Caroline Dani

Neuroscience Letters（2017）

引用 12|浏览12

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摘要

•Maternal choices modulate histone H4 acetylation status in hippocampus of the offspring.•Consumption of grape juice increased this epigenetic mark in adolescents pups.•High-fat diet diminished this epigenetic marker in the adult phase.

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关键词

Epigenetic,Gene expression,Global histone H4 acetylation,Maternal behavior,Polyphenols

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