TDP-43 regulates cancer-associated microRNAs

Protein & cell, 2017.

Cited by: 4|Bibtex|Views10|Links
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Keywords:
TDP-43cancermiRNAmigrationprognosis

Abstract:

Aberrant regulation of miRNA genes contributes to pathogenesis of a wide range of human diseases, including cancer. The TAR DNA binding protein 43 (TDP-43), a RNA/DNA binding protein associated with neurodegeneration, is involved in miRNA biogenesis. Here, we systematically examined miRNAs regulated by TDP-43 using RNA-Seq coupled with an...More

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