Multiplexing molecular tension sensors reveals piconewton force gradient across talin-1

Pia Ringer,Andreas Weißl,Anna-Lena Cost,Andrea Freikamp,Benedikt Sabass, Alexander Mehlich,Marc Tramier,Matthias Rief,Carsten Grashoff

NATURE METHODS（2017）

引用 87|浏览18

暂无评分

摘要

genetically encoded tension sensor module for measuring molecular forces at 3–5 pN along with tools for multiplexed tension sensing and data analysis reveal an intramolecular tension gradient across talin-1 during cell adhesion.

查看译文

关键词

Cell adhesion,Cytoskeleton,Fluorescent proteins,Protein design,Life Sciences,general,Biological Techniques,Biological Microscopy,Biomedical Engineering/Biotechnology,Bioinformatics,Proteomics

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要