Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring

Klaus Eyer,Raphaël C L Doineau,Carlos E Castrillon,Luis Briseño-Roa, Vera Menrath,Guillaume Mottet,Patrick England, Alexei Godina,Elodie Brient-Litzler,Clément Nizak,Allan Jensen,Andrew D Griffiths,Jérôme Bibette,Pierre Bruhns,Jean Baudry

NATURE BIOTECHNOLOGY（2017）

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摘要

n in-droplet immunoassay enables determination of the rate and affinity of secreted antigen-specific antibodies at the single-cell level.

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关键词

Antibodies,Assay systems,Bioanalytical chemistry,Microfluidics,Protein vaccines,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics

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