miR-107-mediated decrease of HMGCS2 indicates poor outcomes and promotes cell migration in hepatocellular carcinoma.

Shu-Guang Su,Mei Yang,Mei-Fang Zhang,Quan-Zhou Peng,Ming-Yue Li,Li-Ping Liu,Shi-Yun Bao

The International Journal of Biochemistry & Cell Biology（2017）

引用 39|浏览8

暂无评分

摘要

•HMGCS2 expression is decreased in HCC and correlated with poor outcomes in two independent cohorts consisting of 743 cases.•HMGCS2 is targeted by miR-107 in HCC cells.•Suppression of HMGCS2 promotes tumor metastasis via ERK/c-Jun signaling pathway.

查看译文

关键词

HMGCS2,miR-107,ERK/c-Jun,Hepatocellular carcinoma

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要