A Gene-Protein-miRNA Electronic Oscillator.

IEEE Transactions on Circuits and Systems II: Express Briefs(2017)

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摘要
This brief presents an electronic oscillator circuit model mimicking a unique relationship among six genes. Three out of the six genes are employed to synthesize proteins, while the remaining three are their complementary micro-ribonucleic acid (miRNA) genes degrading the messenger-RNA transcripts at the translational level of gene expression. The circuit runs without any external stimulus because...
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关键词
Oscillators,RNA,Proteins,Voltage control,Transistors,Integrated circuit modeling
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