Prenatal Stress Induced Gender-specific Alterations of N-Methyl-D-Aspartate Receptor Subunit Expression and Response to Aβ in Offspring Hippocampal Cells.

•Female offspring is more vulnerable to PS-induced cognitive impairment.•PS increased Aβ1-40 levels in DG subregion of male offspring.•The alteration of GluN2A expression in offspring’s hippocampal CA subregion is gender-specific.•PS could alleviate Aβ synaptotoxicity in male offspring’s hippocampal cells.