Neutral merocyanine dyes: for in vivo NIR fluorescence imaging of amyloid-β plaques.
CHEMICAL COMMUNICATIONS(2017)
摘要
Two neutral merocyanine-based near-infrared fluorescent probes were for the first time developed through rational engineering of the classical cationic cyanine scaffold IR-780 for in vivo imaging of amyloid-beta plaques. In vivo NIRF imaging revealed that the probe could penetrate the blood-brain barrier and efficiently differentiate the living transgenic and wild-type mice.
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关键词
Fluorescent Probes
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