Sol gel-derived hydroxyapatite films over porous calcium polyphosphate substrates for improved tissue engineering of osteochondral-like constructs

Acta biomaterialia, Volume 62, 2017, Pages 352-361.

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Keywords:
Calcium polyphosphateScaffoldSol-gel coatingInorganic polyphosphateCalcification of cartilage

Abstract:

Integration of in vitro-formed cartilage on a suitable substrate to form tissue-engineered implants for osteochondral defect repair is a considerable challenge. In healthy cartilage, a zone of calcified cartilage (ZCC) act as an intermediary for mechanical force transfer from soft to hard tissue, as well as an effective interlocking struc...More

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