Social Interaction Modulates the Neuroinflammatory Response to Global Cerebral Ischemia in Male Mice.
Brain Research(2017)
摘要
•Isolation-induced increase of MHC II expression is suggestive of microglial priming.•Social isolation exacerbates the neuroinflammatory response to CA/CPR.•Housing condition prior to an ischemic event is sufficient to modulate inflammation.
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关键词
CA/CPR,OGD,aCSF,rtPCR,MHC II,TNF-α,IL-1β,IL-6,Nfκb,Iba-1
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