Oncogenic signalling pathways in benign odontogenic cysts and tumours.

•The study of benign neoplasms may reveal relevant aspects of malignant progression.•Oncogenic mutations considered drivers of cancers are reported in benign lesions.•The role of oncogenic mutations seems to be context dependent.•Pathogenic mutations affecting the same pathway are seen in different tumours.•Molecular studies can guide therapeutic approaches towards odontogenic lesions.