Adult onset Still's disease-The evidence that anti-interleukin-1 treatment is effective and well-tolerated (a comprehensive literature review).

Seminars in Arthritis and Rheumatism(2017)

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摘要
The literature contains many reports of the use of commercially available anti-IL-1 agents (anakinra/Kineret®, canakinumab/Ilaris®, or rilonacept/Arcalyst®) in treatment-resistant adult-onset Still’s disease (AOSD). These have been widely summarized in many review articles, but a full account of all reports with each of the agents used is not available.
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关键词
AE,AOSD,CI,DMARDs,IL-1 or 1β,MAS,NSAIDs,SAE,SJIA
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