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Mutation-induced Loss of APP Function Causes GABAergic Depletion in Recessive Familial Alzheimer’s Disease: Analysis of Osaka Mutation-Knockin Mice

Tomohiro Umeda,Tetsuya Kimura,Kayo Yoshida,Keizo Takao,Yuki Fujita,Shogo Matsuyama,Ayumi Sakai,Minato Yamashita,Yuki Yamashita,Kiyouhisa Ohnishi,Mamiko Suzuki,Hiroshi Takuma,Tsuyoshi Miyakawa,Akihiko Takashima,Takashi Morita,Hiroshi Mori,Takami Tomiyama

Acta Neuropathologica Communications（2017）

Cited 24|Views44
Key words
Alzheimer’s disease,Recessive mutation,Knockin mouse,Loss of function,GABA
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