Elevated levels of vWF and HMGB1 are associated with disease severity and clinical outcome of scrub typhus.

Hongliu Chen,Zong Ning,Ying Qiu,Yuanli Liao,Haihua Chang, Yuanyuan Ai,Yinghua Wei,Yiming Deng, Ying Shen

International Journal of Infectious Diseases（2017）

引用 9|浏览14

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摘要

•von Willebrand factor (vWF) and high mobility group box 1 (HMGB1) significantly increase in scrub typhus patients and even increase to a larger extent in scrub typhus patients with multiple organ dysfunction syndrome (MODS).•Both vWF and HMGB1 are significantly associated with the mortality of scrub typhus.•vWF and HMGB1 are potential predictors of the severity and outcome of scrub typhus.

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关键词

Scrub typhus,Multiple organ dysfunction syndrome,von Willebrand factor,High mobility group box 1

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