Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30 + Lymphoma.

Jean-Jacques Tudesq,Laure Vincent, Julie Lebrun,Yosr Hicheri,Ludovic Gabellier, Timothé Busetto,Corinne Merle,Nathalie Fegueux,Patrice Ceballos,Philippe Quittet,Robert Navarro,Dominique Hillaire-Buys,Guillaume Cartron

OPEN FORUM INFECTIOUS DISEASES（2017）

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摘要

Brentuximab vedotin is an antibody-conjugated chemotherapy targeting CD30 indicated in treatment of several lymphomas. We report the first 3 cases of cytomegalovirus severe infections with retinitis following this treatment. Evolution was favorable, but relapse occurred after treatment rechallenge. We suggest vigilance about cytomegalovirus in patients treated with brentuximab vedotin.

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关键词

brentuximab vedotin,cytomegalovirus,Hodgkin's lymphoma,retinitis

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