Utilization of an active site mutant receptor for the identification of potent and selective atypical 5-HT2C receptor agonists.
Joseph Carpenter,Ying Wang,Gang Wu,Jianxin Feng,Xiang-Yang Ye,Christian L Morales,Matthias Broekema,Karen A Rossi,Keith J Miller,Brian J Murphy,Ginger Wu,Sarah E Malmstrom,Anthony V Azzara,Philip M Sher,John M Fevig,Andrew Alt,Robert L Bertekap,Mary Jane Cullen, Timothy M Harper,Kimberly Foster,Emily Luk,Qian Xiang,Mary F Grubb,Jeffrey A Robl,Dean A Wacker JOURNAL OF MEDICINAL CHEMISTRY（2017）
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active site mutant receptor,receptor agonists
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