Vitamin D mediates the relationship between placental cathelicidin and group B streptococcus colonization during pregnancy.

Christine C Akoh,Eva K Pressman,Corrie M Whisner,Carrie Thomas,Chang Cao,Tera Kent,Elizabeth Cooper,Kimberly O O'Brien

Journal of Reproductive Immunology（2017）

引用 7|浏览25

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摘要

•Recto-vaginal GBS colonization is associated with lower placental CAMP mRNA.•Placental CAMP mRNA is positively correlated with CYP27B1 mRNA.•Placental CYP27B1 mRNA and cubilin mRNA are lower in those with GBS.•Vitamin D status may increase susceptibility to maternal-fetal infections.

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ANOVA,AMP,BMI,CAMP,LL-37,GA,GBS,HAMP,iPTH,NCBI,RIA,RAMP,TLR,VDBP,VDR,VDRE,CYP27B1,1,25(OH)2D,CYP24A1,CYP2R1,25(OH)D

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