A phase 2 study of momelotinib, a potent JAK1 and JAK2 inhibitor, in patients with polycythemia vera or essential thrombocythemia

Leukemia Research(2017)

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摘要
•Once-daily momelotinib 100mg or 200mg has limited activity in patients with PV/ET.•Predose momelotinib plasma levels were stable throughout the study.•Safety profile was comparable to results reported for momelotinib in myelofibrosis patients.
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关键词
Momelotinib,Polycythemia vera,Essential thrombocythemia,Phase 2 study
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