Detection of yellow fever virus genomes from four imported cases in China.

International Journal of Infectious Diseases(2017)

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摘要
•The clinical features of four imported cases of yellow fever are reported.•Next Generation Sequencing was used to analyze the viral genome in these YF cases.•All viruses were highly homologous with Angola 71 strain and showed no significant mutation compared with YFV-17D vaccine strain.•Urine was firstly used to detect the viral genome in clinic samples.
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关键词
Yellow fever virus,Urine sample,Whole genome sequencing,Phylogenetic analysis,Vaccine effectiveness
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