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Structural Toggle in the RNaseH Domain of Prp8 Helps Balance Splicing Fidelity and Catalytic Efficiency

Megan Mayerle,Madhura Raghavan,Sarah Ledoux,Argenta Price,Nicholas Stepankiw,Haralambos Hadjivassiliou,Erica A. Moehle,Senen D. Mendoza,Jeffrey A. Pleiss,Christine Guthrie,John Abelson

Proceedings of the National Academy of Sciences（2017）

引用 28|浏览38
关键词
spliceosome,Prp8,splicing fidelity,splicing efficiency,lariat sequencing
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