20. Major Cardiovascular Outcomes in the EXAMINE Trial According to ACE Inhibitor Use (12-OR)

    Nederlands Tijdschrift voor Diabetologie, pp. 75-75, 2015.

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    Abstract:

    Activation of the sympathetic nervous system through substance P via DPP-4 inhibition (DPP-4i) in the presence of higher dose ACE inhibition (ACEi) has led to hypothetical concerns of the cardiovascular (CV) safety of these 2 classes of drugs used together. We evaluated adjudicated CV events in EXAMINE, a trial of patients with type 2 dia...More

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