Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution

Gary C H Mo,Brian Ross,Fabian Hertel,Premashis Manna,Xinxing Yang,Eric Greenwald,Chris Booth,Ashlee M Plummer,Brian Tenner,Zan Chen,Yuxiao Wang,Eileen J Kennedy,Philip A Cole,Karen G Fleming,Amy Palmer,Ralph Jimenez,Jie Xiao,Peter Dedecker,Jin Zhang

NATURE METHODS（2017）

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摘要

New fluorescent biosensors enable the first super-resolution imaging of enzyme activity in live cells via fluorescence fluctuation increase by contact (FLINC).

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关键词

Super-resolution microscopy,Phosphorylation,Biosensors

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