A tight tunable range for Ni( II ) sensing and buffering in cells

Andrew W Foster,Rafael Pernil,Carl J Patterson,Andrew J P Scott,Lars-Olof Pålsson,Robert Pal,Ian Cummins,Peter T Chivers,Ehmke Pohl,Nigel J Robinson

NATURE CHEMICAL BIOLOGY（2017）

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摘要

The Ni( ii ) affinity of Ni( ii ) sensor InrS is attuned to buffered Ni( ii ) concentrations, explaining why these two parameters co-vary for different metals over many orders of magnitude.

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关键词

Metalloproteins,Metals,X-ray crystallography,Transcription

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