Genetic and mechanistic diversity of piRNA 3′-end formation

Rippei Hayashi,Jakob Schnabl,Dominik Handler,Fabio Mohn,Stefan L. Ameres,Julius Brennecke

Nature（2016）

引用 128|浏览0

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摘要

Drosophila have two pathways for PIWI-interacting RNA (piRNA) 3′-end formation—depending on which pathway is used, piRNA biogenesis is directed towards either cytoplasmic or nuclear PIWI protein effectors, which balances post-transcriptional versus transcriptional transposon silencing.

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关键词

RNAi,Science,Humanities and Social Sciences,multidisciplinary

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