In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration Keiichiro Suzuki , Yuji Tsunekawa , Reyna Hernandez-Benitez , Jun Wu , Jie Zhu , Euiseok J. Kim , Fumiyuki Hatanaka , Mako Yamamoto , Toshikazu Araoka , Zhe Li , Masakazu Kurita , Tomoaki Hishida , Mo Li , Emi Aizawa , Shicheng Guo , Song Chen , April Goebl , Rupa Devi Soligalla , Jing Qu , Tingshuai Jiang , Xin Fu , Maryam Jafari , Concepcion Rodriguez Esteban , W. Travis Berggren , Jeronimo Lajara , Estrella Nuñez-Delicado , Pedro Guillen , Josep M. Campistol , Fumio Matsuzaki , Guang-Hui Liu , Pierre Magistretti , Kun Zhang , Edward M. Callaway , Kang Zhang , Juan Carlos Izpisua Belmonte NATURE（2016）
摘要
method for CRISPR-based genome editing that harnesses cellular non-homologous end joining activity to achieve targeted DNA knock-in in non-dividing tissues.
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Genetics, Genetic techniques
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