Structural Stability Of Biological Models With Switchings

2016 21ST INTERNATIONAL CONFERENCE ON METHODS AND MODELS IN AUTOMATION AND ROBOTICS (MMAR)(2016)

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摘要
We analyse properties of the control system with switchings in parameters. We consider biological model of proteins production in three variants of the model structure: a simple model without any autoregulation, the one with negative feedback loop and one with positive. In the system we introduce an action of drug in order to decrease proteins number. The drug application is considered as a step change of the protein degradation parameter. The aim of this work is to analyse stability of the model.
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关键词
model stability analysis,protein degradation parameter,drug application,positive feedback loop,negative feedback loop,autoregulation,model structure,proteins production,control system,parameter switching,biological model structural stability
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