Differential effect of chronic stress on mouse hippocampal memory and affective behavior: Role of major ovarian hormones.

Bhanu Chandra Karisetty,Swati Maitra,Abhipradnya Bipin Wahul, Anusha Musalamadugu,Nitin Khandelwal, Sumasri Guntupalli, Ramya Garikapati,Thatiparthi Jhansyrani,Arvind Kumar,Sumana Chakravarty

Behavioural Brain Research（2017）

引用 23|浏览9

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摘要

•Intact and OVX females showed difference in mood disorder sub-phenotypes to CUS.•Estrogen alters hippocampal mood and cognition circuitries in female mice.•Estrogenic effects appear to be mediated via N-methyl-d-aspartate receptor subunits.

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关键词

Depression,Mood disorder,Cognitive disorder,Ovariectomy,17β-Estradiol,NMDAR

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