E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1

Guanhua Song,Bingyu Liu,Zhihui Li,Haifeng Wu,Peng Wang,Kai Zhao,Guosheng Jiang,Lei Zhang,Chengjiang Gao

NATURE IMMUNOLOGY（2016）

引用 134|浏览14

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摘要

Gao and colleagues show that the T cell anergy–related E3 ubiquitin ligase RNF128 is a positive regulator of TBK1 activation and interferon-β production.

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关键词

Innate immunity,Cell biology

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