Absence of CALR mutations in JAK2-negative polycythemia.

Aurélie Chauveau,Olivier Nibourel,Sylvie Tondeur,Damien Luque Paz,Olivier Mansier,Franciane Paul,Mathieu Wemeau,Claude Preudhomme,Eric Lippert,Valérie Ugo

Haematologica（2016）

引用 14|浏览34

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摘要

Polycythemia vera (PV) is a myeloproliferative neoplasm (MPN) responsible for increased hematopoiesis, mainly affecting the erythroid lineage. The diagnosis of PV has been simplified enormously by the description of JAK2 mutations, affecting the canonical V617 in exon 14 in more than 95% of cases,

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