Depot specific differences in the adipogenic potential of precursors are mediated by collagenous extracellular matrix and Flotillin 2 dependent signaling.

Gerald Grandl,Sebastian Müller,Hansjörg Moest,Caroline Moser,Bernd Wollscheid,Christian Wolfrum

Molecular Metabolism（2016）

引用 27|浏览8

暂无评分

摘要

•Different adipose tissue depots have different differentiation capacities.•Differentiation of preadipocytes is enhanced by vitamin c through formation of collagenous ECM.•Collagenous ECM is the main determinant of adipose depot specific differences in adipogenic potential.•FLOT2 plays a role in mediating collagenous-ECM specific effects.

查看译文

关键词

Adipocyte precursors,Extracellular matrix,Collagen,Stem cell niche,Flotillin 2

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要