The kinase CK1ɛ controls the antiviral immune response by phosphorylating the signaling adaptor TRAF3

Yilong Zhou,Chenxi He,Dapeng Yan,Feng Liu,Haipeng Liu,Jianxia Chen,Ting Cao,Mianyong Zuo, Peng Wang,Yan Ge,Haojie Lu,Qinghe Tong,Chengfeng Qin,Yongqiang Deng,Baoxue Ge

Nature immunology（2016）

引用 27|浏览6

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摘要

Type I interferons suppress viral infection. Ge and colleagues show that the kinase CK1ɛ contributes to this innate immune response by phosphorylating the signaling adaptor TRAF3 to facilitate the expression of type I interferons.

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关键词

Signal transduction,Infection

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