Consequences of constitutive deletion of melanin-concentrating hormone-1 receptors for feeding and foraging behaviors of mice.

William J A Eiler,Yanyun Chen,Lawrence J Slieker,Paul A Ardayfio,Michael A Statnick,Jeffrey M Witkin

Behavioural Brain Research（2017）

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摘要

•MCH1 −/− mice exhibited increased motivation to obtain food compared to WT mice.•Increased food-seeking in MCH1−/− mice was also observed when behavior was punished.•Feeding in MCH1 −/− mice contrasts in some important dimensions from data reported with MCH1 receptor antagonism.

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关键词

MCH1,Feeding,Motivation,Mouse

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