Sesquiterpenes from the roots of Lindera strychnifolia with inhibitory effects on nitric oxide production in RAW 264.7 cells.

Qing Liu,Yang Hee Jo,Seon Beom Kim,Qinghao Jin,Bang Yeon Hwang,Mi Kyeong Lee

Bioorganic & Medicinal Chemistry Letters（2016）

引用 12|浏览13

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摘要

Seven new sesquiterpenes, linderolides N–T (1–7), along with nine known compounds, were isolated from roots of Lindera strychnifolia. Linderolide O (2) and P (3) inhibited lipopolysaccharide-stimulated nitric oxide production with IC50 values of 6.3 and 9.6μM, respectively.

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关键词

Lindera strychnifolia,Lauraceae,Sesquiterpene,Linderolides N–T,Anti-inflammation

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