YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells
NATURE NEUROSCIENCE(2016)
摘要
Cells respond to mechanical signals during development and after injury. Poitelon et al . report for the first time that myelin-forming glia activate the Hippo pathway effectors Yap and Taz in response to mechanical stimuli, and that they are required for Schwann cell development and myelination in vivo .
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关键词
Glial development,Myelin biology and repair,Schwann cell
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