An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2016）

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摘要

The solution structure of the J-K region of the EMCV IRES establishes a preorganized recognition mode for hijacking translation initiation factor 4G.

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关键词

Solution-state NMR,SAXS,RNA,Translation

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