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Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

Amalie Kai Bentzen,Andrea Marion Marquard,Rikke Lyngaa,Sunil Kumar Saini,Sofie Ramskov,Marco Donia, Lina Such,Andrew J S Furness,Nicholas McGranahan,Rachel Rosenthal,Per thor Straten,Zoltan Szallasi,Inge Marie Svane,Charles Swanton,Sergio A Quezada,Søren Nyboe Jakobsen,Aron Charles Eklund,Sine Reker Hadrup

NATURE BIOTECHNOLOGY（2016）

引用 231|浏览32
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摘要
Detection of more than 1,000 different T-cell specificities in parallel facilitates identification of cancer and autoimmune antigens.
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关键词
CD8-positive T cells,Tumour immunology,Immunological techniques,High-throughput screening,MHC class I
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