Statistical Shape Modeling Of Compound Musculoskeletal Structures Around The Thigh Region

Accurate 3D models of lower extremity are required for model-based simulations in kinematic analysis of musculoskeletal (MS) system. In this paper, we present a modeling framework which combines a hybrid registration scheme with an articulated statistical shape model (aSSM) construction technique. The present modeling framework is used to develop an aSSM of compound MS structures based on a training set of 12 single side CT images with the associated ground-truth segmentation of 7 structures around the thigh region. By incorporating 90% of the training set variations, the model exhibits a generalization ability of 2.77 +/- 0.48 mm and specificity of 2.87 +/- 0.43 mm. The constructed aSSM has potential applications in model-based 2D-3D construction, 3D medical image segmentation, and kinematic analysis of MS system. To the best of our knowledge, this is the first 3D aSSM of compound MS structures around the thigh region.