An Impedance Detection Circuit For Applications In A Portable Biosensor System

As the world's population ages, healthcare costs become heavy burdens worldwide. Portable point-of-care diagnostic devices, such as glucose meters, can significantly reduce the costs associated with patient care. There are many of small biological molecules present in biological samples which are of interest in healthcare applications. In this paper, a simple low-cost impedance detection circuit has been designed to detect different biomolecules such as DNA, proteins and other metabolites. In particular, the impedance across an electrode will change due to the binding of target biomolecules and gold nanoparticles. Experimental results show that the device can measure impedance changes with accuracy in the range of +/- 3%.