An Enhanced Genetic Algorithm for Ab Initio Protein Structure Prediction.

IEEE Transactions on Evolutionary Computation(2016)

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摘要
In-vitro methods for protein structure determination are time-consuming, cost-intensive, and failure-prone. Because of these expenses, alternative computer-based predictive methods have emerged. Predicting a protein's 3-D structure from only its amino acid sequence-also known as ab initio protein structure prediction (PSP)-is computationally demanding because the search space is astronomically lar...
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关键词
Proteins,Amino acids,Lattices,Three-dimensional displays,FCC,Genetic algorithms,Solid modeling
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