Base-resolution profiling of active DNA demethylation using MAB-seq and caMAB-seq

Nature Protocols（2016）

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摘要

This protocol for methylase-asssisted bisulfite sequencing (MAB-seq) and caMAB-seq allows the analysis of active DNA demethylation, directly mapping 5fC and 5caC at single-base resolution.

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关键词

DNA methylation,Epigenomics,Methylation analysis,Next-generation sequencing

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