Purine metabolism is dysregulated in patients with major depressive disorder.

Toni Ali-Sisto,Tommi Tolmunen,Elena Toffol,Heimo Viinamäki,Pekka Mäntyselkä,Minna Valkonen-Korhonen,Kirsi Honkalampi,Anu Ruusunen,Vidya Velagapudi,Soili M Lehto

Psychoneuroendocrinology（2016）

引用 82|浏览11

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摘要

•Decreased serum levels of inosine and guanosine were associated with depression.•Depressed patients also displayed increased serum levels of xanthine.•Purine metabolite alterations did not change during recovery from depression.

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关键词

Major depressive disorder,Metabolomics,Purine metabolism,Inosine,Guanosine,Xanthine

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