Lipid Rescue - Efficacy and Safety Still Unproven.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY(2016)

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摘要
Intralipid(®) , the soybean oil-based nutritional lipid emulsion for intravenous administration, has maintained a remarkably safe record for more than 50 years. In conventional use, its rare adverse effects consist of pancreatitis, hepatic failure, dyspnoea and anaphylaxis, and these are usually due to overdose or too rapid infusion rate [1, 2]. Intralipid(®) , and other similar stable lipid emulsions have also pharmaceutical application as vehicles for various drugs such as diazepam, etomidate and propofol. This article is protected by copyright. All rights reserved.
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