Predictive value of BRCA1 expression on the efficacy of chemotherapy based on anti-microtubule agents: a pooled analysis across different malignancies and agents

Qihua He
Qihua He
Jianrong Zhang
Jianrong Zhang
Shengyi Zhong
Shengyi Zhong
Yuan Zeng
Yuan Zeng
Minzhang Guo
Minzhang Guo
Xuewei Chen
Xuewei Chen

ANNALS OF TRANSLATIONAL MEDICINE, pp. 110-110, 2016.

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Keywords:
Breast cancer susceptibility gene 1 (BRCA1)anti-microtubule agentsmeta-analysis

Abstract:

Background: Breast cancer susceptibility gene 1 (BRCA1) expression has been suggested as a predictor in antineoplastic treatment with anti-microtubule agents. However, the existing evidence is conflicting. Consulting the literature, we sought to examine the true impact of BRCA1 expression on the efficacy of anti-microtubule agents. Method...More

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