Innate-like functions of natural killer T cell subsets result from highly divergent gene programs

Isaac Engel,Grégory Seumois,Lukas Chavez,Daniela Samaniego-Castruita,Brandie White,Ashu Chawla, Dennis Mock,Pandurangan Vijayanand,Mitchell Kronenberg

NATURE IMMUNOLOGY（2016）

引用 236|浏览32

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摘要

Invariant natural killer T cells recognize lipid antigens presented by CD1d molecules and are capable of copious cytokine production. Kronenberg and colleagues show that distinct transcriptional and epigenetic profiles can be ascribed to the NKT1, NKT2 and NKT17 subsets of these cells.

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关键词

Epigenetics in immune cells,Innate immune cells

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