Pooled-sera hSBA titres predict individual seroprotection in infants and toddlers vaccinated with 4CMenB.

Sonia Budroni,Annett Kleinschmidt,Philip Boucher,Duccio Medini

Vaccine（2016）

引用 20|浏览1

暂无评分

摘要

The Serum Bactericidal Antibody assay with human complement (hSBA) using individual immune sera is a surrogate of protection for meningococcal vaccines. Strain coverage of 4CMenB, a licensed vaccine against serogroup B meningococcal (MenB) disease, has been extensively assessed in hSBA using pooled sera, directly or through the Meningococcal Antigen Typing System (MATS). The extent to which pooled-sera hSBA titres reflect individual protection is not yet fully understood.

查看译文

关键词

Surrogate of protection,Serum Bactericidal Antibody Assay with human complement hSBA,Pooled sera,Meningococcal disease,4CMenB Vaccine

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要