C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases.

Anne K Braczynski,Patrick N Harter,Pia S Zeiner,Ulrich Drott,Dominique-Suzanne Tews,Corinna Preusse, Cornelia Penski,Maika Dunst,Joachim Weis,Werner Stenzel,Michel Mittelbronn

Neuromuscular Disorders（2016）

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摘要

•Endomysial capillary C5b-9 deposits are rather unspecific for dermatomyositis (DM).•Classical DM cases show capillary C5b-9 accumulation in a perifascicular pattern.•C5b-9-positive non-DM cases display rather diffuse endomysial capillary C5b-9 deposits.•60% of non-DM cases with C5b-9-positive capillaries suffered from auto-immune diseases.•Endomysial capillary C5b-9 deposits are a marker for (auto-) immune diseases.

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关键词

C5b-9,Microvascular unit,Muscle disease,Dermatomyositis,MHC-I

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