Diacrylamides as selective G-quadruplex ligands in in vitro and in vivo assays

Adam Le Gresley,Ammara Abdullah, Deepak Chawla,Pratchi Desai,Uttam Ghosh,Uma Gollapalli,Munazza Kiran,Shehri Lafon,A Sinclair

MEDCHEMCOMM（2011）

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摘要

The synthesis of previously unreported anthracene-9-monoacrylamides and anthracen-9,10-bisacrylamides and their potential as G-quadruplex ligands, based on preliminary fluorometric and biological assay data, is discussed.

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chemistry,pharmacy

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