Efficient synthesis and resolution of novel 2-(hydroxymethyl)-7,8-dihydro-1 H -indeno[5,4- b ] furan-6(2 H )-one by lipase Pseudomonas cepacia

Lingaiah Nagarapu,Hanmanth Reddy Vulupala,Rajashaker Bantu,Yashodakrishna Sajja,Jagadeesh Babu Nanubolu

Tetrahedron: Asymmetry（2014）

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摘要

Synthesis and enzymatic resolution of novel 2-(hydroxymethyl)-7,8-dihydro-1H-indeno[5,4-b] furan-6(2H)-one using vinyl acetate as the acyl donor in acetone is reported first time.

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