Design, Synthesis, And Biological Evaluation Of Beta-Carboline Dimers Based On The Structure Of Neokauluamine

Jaruwan Chatwichien,Jeffrey Winkler,Maureen Murphy,Mark Hamann,Subhasree Basu

TETRAHEDRON LETTERS（2015）

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摘要

The design, synthesis, and biological evaluation (anticancer and antimalarial activity) of bis-beta-carbolines, based on the structure of the naturally occurring alkaloid neokauluamine, is described. (C) 2015 Elsevier Ltd. All rights reserved.

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关键词

Manzamine alkaloids,Structure-activity relationships (SAR),beta-Carboline heterocycle

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